
Repair | Regeneration support
PDRN
This is a regenerative skin therapy that uses PN and PDRN derived from purified salmon DNA.
About PDRN
Salmon DNA to your skin’s rescue? Believe it, this is real! Yoyime’s PDRN treatment is a scientifically backed, natural skin booster procedure with effective long-term results. It harnesses the power of Polynucleotides (PN) and PDRN (polydeoxyribonucleotide) derived from purified salmon DNA to activate the skin's deepest repair mechanisms. When injected into the dermal layers, these bio-stimulating DNA fragments activate A2A receptors which then stimulate fibroblast activity and trigger increased production of collagen, elastin and natural hyaluronic acid. The result? Over a few sessions, a progressive cellular regeneration that visibly improves hydration, elasticity, firmness and overall skin quality from within. What more can one ask for?
Effects of PDRN Treatment
Deep Skin Hydration
Improves Skin Texture
Reduces Sun Damage
Not Recommended for Patients

Who Are Pregnant

With Fish Allergy

With Skin Inflammation
Tools and Equipment for PDRN

Step-by-Step Procedure PDRN Treatment
Consultation & Skin Assessment
Your journey starts with a detailed consultation where your skin condition, concerns and goals are evaluated. Our specialist then designs a personalised treatment plan based on your needs.

Skin Cleansing & Preparation
The treatment area is thoroughly cleansed and disinfected using antiseptic wipes to prepare the skin for the procedure and ensure safety.

Marking the Treatment Area
The practitioner maps and marks the specific injection points based on a targeted pattern to ensure even and accurate placement.

Topical Numbing Application
A topical anaesthetic cream is applied to the area and left for about 20–30 minutes to minimise discomfort during the procedure.

PDRN Micro-Injections
Using ultra-fine needles, PDRN (polynucleotides derived from salmon DNA) is injected into the dermal layers. The injections are placed at evenly spaced, pre-marked points to ensure uniform distribution and optimal skin regeneration.

Soothing Skin
Immediately after injections, a cooling mask, soothing serum or gel is applied to calm the skin and reduce redness or sensitivity.

Aftercare Guidance
The practitioner assesses the skin for any redness or reaction before you leave. You are then given detailed aftercare instructions to support healing and maximise results.

Have questions about PDRN?
Message our team on WhatsApp for personalised guidance before you book.
- Highly specialised and focused treatment techniques
- Personalised care by DHA certified professionals
- Comfort-driven experience with proven results
- Safe, convenient and effective
Frequently Asked Questions
PDRN
PDRN targets fine lines, acne scars, dull skin, under-eye concerns, uneven texture, sun damage and loss of firmness by stimulating skin regeneration and repair.
Common areas include the full face (forehead, cheeks, nose, temples, chin), under-eyes, lips, neck, décolletage and hands for hydration, texture and elasticity improvement.
Pregnant or nursing individuals, those with active skin infections, autoimmune skin conditions or blood-thinning medication users should avoid this treatment. Individuals with known allergy to fish or salmon-derived ingredients as well.
Yes, PDRN treatment is biocompatible, biodegradable and derived from purified salmon DNA, making it highly safe with a very low risk of allergic reaction when performed in a clinical setting.
Yes, it is generally suitable for sensitive and reactive skin because it is gentle, healing and supports inflammation reduction and skin repair.
Most patients require 3–5 sessions spaced 1–3 weeks apart or a standard course of 3–4 sessions spaced 2–4 weeks apart, depending on the clinic protocol and skin condition.
Some improvement can appear after the first sessions, but results gradually build over several weeks as collagen production and cellular regeneration increase.
Results typically last around 3–6 months, with maintenance sessions recommended every few months to sustain improvements.
Downtime is minimal. Most patients return to normal activities immediately, though mild redness, swelling or sensitivity may occur temporarily.
Mild redness, swelling or slight bruising at injection sites can occur but usually resolve within a few days.
Discomfort is minimal. A numbing cream is usually applied and injections are done with fine needles to reduce sensation.
Avoid blood-thinning medications and supplements (like aspirin, fish oil, vitamin E) for 5–7 days. Avoid alcohol for 24–72 hours, stop harsh skin treatments 1–2 weeks prior, arrive with clean skin, stay hydrated and avoid intense exercise 24 hours before.
Makeup can usually be applied after 24–48 hours, depending on skin sensitivity and healing.
Avoid touching or rubbing the skin, alcohol, saunas, steam rooms, hot showers, intense exercise and sun exposure for at least 24–48 hours.
A typical PDRN session takes around 20–30 minutes, making it suitable for busy schedules.
At Yoyime Clinic, our PDRN Salmon Treatment Dubai utilizes purified salmon DNA fragments to stimulate cellular repair, deep hydration and essential collagen production from within. This advanced, non-invasive regenerative therapy effectively restores skin elasticity and firmness, delivering progressively smoother, healthier and more radiant skin as your natural healing response activates.
Of course. Our clinic has 5-star ratings and Yoyime Clinic is one of the most searched clinics online for such treatments. Searches for ‘PDRN Facial’ and ‘PDRN Injection’ will also show similar results.







